- U.S. Navy:
SV was contracted to prepare the NAF Atsugi
Toxicological Assessment, which involved developing toxicity
values for 86 chemicals that did not have USEPA-verified
toxicity values. After
developing the toxicity values de novo based on an
exhaustive toxicity assessment, a risk assessment was performed
for three sites at NAF Atsugi.
- U.S. Navy:
SV developed detailed human health risk assessment
guidance for polychlorinated biphenyls.
A structure-activity relationship was used to develop
unique toxicity values for PCB congeners.
- U.S. Navy:
Performed toxicological assessments of 13 chemicals,
- U.S. EPA:
SVís Dr. DeGrandchamp was selected by USEPA to
represent the agency in trial because USEPA needed a nationally
recognized toxicologist to develop a new toxicological paradigm
for dioxin-like PCB congeners that currently do not have USEPA-verified
toxicity values. Dr.
DeGrandchamp developed a toxic equivalency factor (TEF) approach
based on the structure activity relationship of mono- and non-ortho
substituted PCBs where each of the 12 individual PCB congeners
was assigned a toxicity value relative to the toxicity of TCDD.
- U.S. Navy, Office of the General Counsel:
SVís Dr. DeGrandchamp was retained by the Office of
General Counsel, Naval Sea Systems Command, to provide
toxicological expert support in a case involving more than 6,000
individuals who claimed medical injuries from putative Navy
chemical releases. Dr.
DeGrandchamp conducted a toxicological analysis of several
chemicals using hair analysis results.
As part of this toxicological assessment, Dr.
DeGrandchamp evaluated the potential risks associated with
mercury-induced brain damage based on hair samples provided by
the plaintiff experts. This
was based on correlations between in utero blood levels
in umbilical cord and hair.
As part of this analysis, Dr. DeGrandchamp used currently
accepted scientific principles; peer-reviewed references; and
USEPA, World Health Organization (WHO), and National Academy of
Sciences (NAS) guidelines to address data gaps in previous
studies in order to refute another expertís findings.
Department of Justice, Expert Witness Unit:
SVís Dr. DeGrandchamp was retained by USDOJ and
worked with USEPA Region VIII to conduct a multifaceted
toxicological and epidemiological assessment of worker-related
human health risks. During this complex and multifaceted study, Dr.
DeGrandchamp assessed risks from numerous chemicals using many
toxicity databases, evaluated the toxicity based on blood sample
results from the workers, and conducted a toxicological review
of their medical records as part of an epidemiological study.
Review of workersí medical records showed they were
experiencing a higher-than-normal prevalence of
chemical-specific toxic effects.
Navy: SV prepared and delivered a Standard Operating
Procedure (SOP) for conducting a lead risk assessment and
Navy: SV conducted a background analysis implementing
Procedural Guidance for Statistically Analyzing Environmental
Background Data, which Dr. DeGrandchamp authored for the Navy,
at NAS Whiting (Milton Florida). This approach is being
used to identify chemicals of concern for risk assessment,
evaluate Applicable or Relevant and Appropriate Requirements (ARAR),
and identify chemical releases. Successful completion of
this project is expected to save DOD and the state of Florida
$30 million in potential remediation costs.
D.C.: SV conducted a comprehensive risk assessment
involving vapor intrusion into approximate 500 homes from
contaminated groundwater at a site in Washington D.C for the
District Department of the Environment (DDOE). SV is also
developing the risk assessment portion of DDOEís regulation
for stormwater reuse and is the technical expert developing the
Districtsí risk-based approach to protect children from dry
cleaner-related tetrachloroethylene exposures.
Region VIII: SV provided EPA Region VIII with
toxicological and risk assessment technical support at two RCRA
sites involving hazardous solvent exposure to off-site
residents. Responsible for evaluating risks and health
hazards associated with vapor entering homes from contaminated
groundwater into nearby homes. SV was responsible for
evaluating current toxicological peer-reviewed toxicological
studies on formaldehyde to identify current health problems
among residents, determining acceptable levels of exposure, and
identifying homes that may require interim measures or
evacuation of residents.
Navy: SV conducted a comprehensive review and analysis
of diverse scientific methods used to evaluate risks associated
with lead exposure for DON and prepared a Navy position paper
that evaluated all lead risk assessment models, including the
scientific veracity of the U.S. EPA Integrated Exposure Uptake
Biokinetic Model (IEUBK) software code, the California
Lead Spread Model, and the new probabilistic Integrated
Stochastic Model to make recommendations for improvement.
Developed DON risk assessment strategy to evaluate adult lead
exposure in order to expedite lead cleanup at closing Naval
Support and Expert Witness Testimony
- U.S. Department of Justice, Expert Witness Unit, Metal Bank
Superfund Site: SV
conducted a toxicological evaluation/human health risk
assessment, prepared toxicology expert report, and testified as
the Toxicological Expert Witness in two trials.
SVís Dr. DeGrandchamp testified to the veracity of
toxicity values that were used in expert reports.
Dr. DeGrandchamp was retained as an expert witness by
USDOJ, on behalf of USEPA Region III, to prepare an expert
report on the toxicity of dioxins, furans, and PCBs.
In the first phase of the trial, the defendants retained
two expert toxicologists who prepared expert reports on the
toxicity of these three groups of chemicals.
In response to these two expert reports, USEPA
headquarters requested that Dr. DeGrandchamp develop a rebuttal
report reanalyzing these compounds, which only have provisional
toxicity values. In
this rebuttal report, Dr. DeGrandchamp presented his
toxicological evaluation and concluded that the opposing
expertís toxicity assessment was not based on the most recent
toxicological data and information.
The study Dr. DeGrandchamp performed, as well as the
rebuttal report, were extensively reviewed and approved by USEPA
the court found that Dr. DeGrandchampís toxicological
evaluation was the more scientifically tenable and supported by
the latest scientific information, and ruled in favor of USEPA
for $25 million.
- U.S. Department of Justice, Expert Witness
Unit, AK Steel Superfund Site:
SV completed an HHRA that was part of an expert
report Dr. DeGrandchamp prepared as the testifying expert, and
involved a massive release of PCBs into a stream, contaminating
thousands of fish. This study involved conducting a toxicity assessment of
PCBs, dioxins, and furans, and using the information to estimate
the human health risks associated with direct contact with soils
and sediments, as well as from eating fish.
At the request of Dr. DeGrandchamp, USEPA caught and
analyzed fish tissue to measure chemical levels in fish.
The toxicity assessment he prepared was particularly
important because there is considerable controversy surrounding
the toxicity of PCBs, and USEPA has not yet derived verifiable
toxicity values for individual PCB congeners.
This toxicity assessment and the toxicity values that
were developed have undergone extensive USEPA review and were
approved by USEPA headquarters.
As a result of Dr. DeGrandchampís toxicity assessment
and expert report, the plaintiffís attorneys retained eight
nationally recognized toxicologists to rebut his expert opinion,
and he is currently preparing a supplemental expert report and
preparing for deposition and expert witness testimony in trial.
- U.S. Department of Justice, Expert Witness
Unit, U.S. Magnesium Corporation Superfund Site: An extensive toxicology assessment of workers was
conducted and expert witness reports prepared based on human
health risk assessments and review of medical records of
conjunction with NIOSH, blood samples were collected to measure
biomarkers of exposure in blood.
The project required evaluation and verification of the
provisional toxicity value for dioxin and PCBs.
- U.S. Navy, Office of the General Counsel:
SV provided toxicology reports for the Navy, which
was engaged in toxic tort litigation regarding Vieques.
Evaluated the toxicity of several chemicals using
biomarkers in hair samples. A toxicity value for mercury using biomarkers in hair
was used to calculate risk based on recent toxicological
Provided toxicological expertise and negotiation
support; prepared position papers; developed the Navyís
overall remediation strategy; negotiated with local, state, and
federal regulatory agencies; and provided technical expertise in
numerous negotiations and dispute resolution meetings.
Negotiated a geochemical method for evaluating background
conditions in the state of Florida for the Department of Defense
(Navy). After conducting a pilot study to demonstrate that
the geochemical technique can be used to define background
conditions and identify chemical release areas, the Florida
Department of Environmental Protection (FDEP) formally approved
the technique for use on Superfund and Federal Facilities
Conducted numerous baseline risk assessments at Naval Air
Station (NAS) Lemoore in California. These risk
assessments were ultimately combined into a comprehensive
installation-wide risk assessment that involved fate and
transport modeling of contaminants, coupled with the analysis of
current and potential future health risks. Responsible for
all negotiations with federal and state regulators, and
successfully negotiated cost-effective management of human
health risks during remedy selection by using a risk-based
approach to avoid unnecessary and expensive remediation.
Conducted all risk assessments and coordinated feasibility
studies for NAS Moffett Field in California. Carried out a
detailed future land use analysis that was used to focus risk
mitigation strategies based on probable future land use.
The land use analysis was also used to focus human health risk
assessments on realistic exposure conditions to avoid
unrealistic conservative default assumptions. Negotiated
all aspects of the risk assessment approach with state and
federal regulatory agencies. The Navy requested that Dr.
DeGrandchamp assist the Department of Justice in order to avert
formal dispute resolution.
Conducted risk assessments for NAS Alameda in California,
and responsible for developing the overall risk assessment
approach and negotiating all technical aspects of the Navy
project with local, state, and federal regulators. Tasked
with preparing innovative approaches to establish anthropogenic
and nonanthropogenic background conditions, preliminary
remediation goals, and data aggregation to estimate
exposure-point chemical doses. Responsible for developing
a Navy policy document for risk-based corrective action (RBCA)
at petroleum sites.
Force, Lowry AFB: Attended meetings/negotiations with
the Colorado Department of Public Health and the Environment (CDPHE);
provided legal non-testifying expert support to Air Force
attorneys; developed sampling and analysis plans for
contaminated areas and activity-based sampling; conducted
statistical analyses on areas of concern; developed risk
management protocols and evaluated several novel approaches
based on new analytical procedures to expedite decision-making;
conducted field investigations; reviewed extensive
epidemiological studies to evaluate toxicological endpoints; and
calculated health risks and prepared risk assessment reports.
Department of Environmental Protection: Provided
technical expertise to the Massachusetts Department of
Environmental Protection for radionuclide risk assessments, compliance, and cleanup
standards. Worked with the state to develop state guidance
for radionuclide cleanup of all Department of Defense and
Nuclear Regulatory Commission operated sites within the state.
Region VIII: Provided oversight and technical support
to the EPA Region VIII (Montana office) RCRA division for
remediation of oil refineries in Billings, Montana; Mandan,
North Dakota; and Commerce City, Colorado. Oversaw all
phases of the RCRA process involving preliminary investigations
and corrective measures studies, developed health-protective
cleanup levels, and evaluated facility permitting and
remediation enforcement. Worked together with Colorado
Department of Health officials to negotiate remediation goals
and a cost settlement.
Scientia Veritas Statement of Qualifications
Please feel free to contact us for more
information at Toxicology@scientiaveritas.com.